Paper of the Month May 2020

Assessment of Therapy-Related Myeloid Neoplasms in Patients With Neuroendocrine Tumors After Peptide Receptor Radionuclide Therapy- A Systematic Review

This paper, from the Mayo Clinic Cancer Center, presents the results of a systematic literature review of the incidence of therapy-related myeloid neoplasm (t-MNN) as a potential long-term and frequently lethal adverse event after PRRT. 7334 patients treated with PRRT (Lu177 and Y90 mixed up) were included in the analysis.  It was found that the incidence of t-MN was variable between studies with mean (SD) incidence of 2.61% (4.38%).

FANC/AFCN decision personal license

Recognizing current operational challenges, the FANC/AFCN has decided to exempt doctors who use ionising radiation in medicine from the continuous training necessary for the renewal of their license, as far as the year 2020 is concerned. In addition, it has been decided that all physicians using ionising radiation in medicine whose license expires between 13 March 2020 and 31 August 2020 will see their license automatically extended for 6 months.

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Recommendations for performing V/Q scans in the context of COVID-19

Substituting ventilation scintigraphy by CT as part of stand-alone perfusion SPECT/CT is not recommended, as this reduces the specificity of the study. Both perfusion and ventilation studies should be performed to rule out pulmonary embolism.

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